Today it is possible to use DNA sequencing to improve prognostication and predict treatment response in patients with the most common form of leukemia; chronic lymphocytic leukemia. New results from a research group lead by SciLifeLab faculty member Richard Rosenquist Brandell shows that next-generation sequencing technology can provide equally reliable results as previous methods. The new technique could thus be used routinely for prognostication in chronic lymphocytic leukemia.